Purinergic agonists flex vas deferens muscle

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منابع مشابه

The purinergic component of human vas deferens contraction.

OBJECTIVE To examine purinergic signaling in human vas deferens. DESIGN To study contractile responses of the scrotal vas deferens. SETTING Research department of a university teaching hospital. PATIENT(S) Undergoing vasectomy or orchidectomy (aged 27-88 years, n = 14). INTERVENTION(S) Vasectomy or orchidectomy. MAIN OUTCOME MEASURE(S) Strips of vas deferens were suspended in an organ...

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Facilitation of the purinergic contractile response of the guinea pig vas deferens by sodium orthovanadate.

Experiments were carried out to examine the effects of protein tyrosine kinase (PTK) and protein tyrosine phosphatase inhibitors on the purinergic contraction of the guinea pig vas deferens. Sodium orthovanadate (SOV) produced a robust increase of the amplitude of contractions evoked by both neurogenic electrical field stimulation and exogenous ATP. This effect of SOV was concentration- and tim...

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Purinergic contraction of the rat vas deferens in L-NAME-induced hypertension: effect of sildenafil.

Hypertension (HTN) is a risk factor for erectile dysfunction, but its effect on vas deferens (VD) contractility and the ejaculatory response has not been delineated. NG-nitro-L-arginine methyl ester (L-NAME), a nitric oxide synthase inhibitor, was used for induction of nitric oxide (NO)-deficient HTN. Our aim was to evaluate the effects of L-NAME-induced HTN on rat VD contractility and to deter...

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[Congenital unilateral absence of the vas deferens].

A 10-year-old boy with cystic fibrosis (CF) (DeltaF508/G551D mutation) underwent an uneventful elective interval laparoscopic appendectomy. During routine laparoscopic inspection of the abdomen and groins, congenital bilateral absence of the vas deferens was noted. Pictures of the patient's internal inguinal ring noted at time of laparoscopy are presented and compared with a similar-aged patien...

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Robotic Male Vas Deferens Intraluminal Injection System

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ژورنال

عنوان ژورنال: The Journal of Physiology

سال: 2008

ISSN: 0022-3751

DOI: 10.1113/jphysiol.2008.164350